Clinical Resources
ADHD
Addiction
Alzheimers Disease
Anxiety
Appetite
Arthritis
Asthma
Autism
Autoimmune
Batten Disease
Breast Cancer
Cancer
Cannabidiol
Cardiovascular
CB1 - Receptor
CB2 - Receptor
ADHD
Addiction
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Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence.
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Cannabidiol (CBD) in cannabis does not impair driving, landmark study shows.
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Interactions between Δ(9)-tetrahydrocannabinol and heroin: self-administration in rhesus monkeys.
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Involvement of the endocannabinoid system in drug addiction.
Alzheimer's Disease
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A Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology.
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Cannabinoids and Dementia: A Review of Clinical and Preclinical Data.
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Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic.
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Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia.
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Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview.
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Synthetic Cannabinoids in Dementia with Agitation: Case Studies and Literature Review.
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The influence of cannabinoids on generic traits of neurodegeneration.
Anxiety
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Action of cannabidiol on the anxiety and other effects .produced by delta 9-THC in Normal Subjects.
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Is cannabis treatment for anxiety, mood, and related disorders ready for prime time?
Appetite
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Endocannabinoids, feeding and suckling – from our perspective.
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Endogenous cannabinoid system as a modulator of food intake.
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Hypothalamic POMC neurons promote cannabinoid-induced feeding.
Arthritis
Asthma
Autism
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Alterations in the endocannabinoid system in the rat valproic acid model of autism.
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Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling.
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Endocannabinoid System as Novel Therapeutic Target for Autism Treatment.
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Method for predicting autism spectrum disorders by cannabinoid and cannabinoid receptor expression.
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Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome.
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Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces.
Autoimmune
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Cannabidiol arrests onset of autoimmune diabetes in NOD mice.
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Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
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Cannabis use in people with Parkinson’s disease and Multiple Sclerosis: A web-based investigation.
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Endocannabinoids and the Immune System in Health and Disease.
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Endocannabinoid system acts as a regulator of immune homeostasis in the gut.
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Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly.
Batten disease
Breast Cancer
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Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
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Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.
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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
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The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
Cancer
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A Cannabinoid Quinone Inhibits Angiogenesis by Targeting Vascular Endothelial Cells.
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Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors.
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Anti-proliferative effects of anandamide in human hepatocellular carcinoma cells.
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Cannabidiol (CBD) Priming Enhances Cisplatin Killing Of Cancer Cells.
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Cannabidiol Inhibits Growth and Induces Programmed Cell Death in Kaposi Sarcoma.
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Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
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Cannabinoid-associated cell death mechanisms in tumor models.
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Cannabinoid receptor ligands as potential anticancer agents — high hopes for new therapies?
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Cannabinoid receptors as novel targets for the treatment of melanoma.
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Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators.
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COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells.
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Differential role of cannabinoids in the pathogenesis of skin cancer.
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Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders.
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Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion.
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Expression and Functional Relevance of Cannabinoid Receptor 1 in Hodgkin Lymphoma.
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Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma.
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In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
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Involvement of PPARc in the antitumoral action of cannabinoids on hepatocellular carcinoma.
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Loss of cannabinoid receptor 1 accelerates intestinal tumor growth.
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Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers.
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Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid.
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Proapoptotic effect of endocannabinoids in prostate cancer cells.
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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
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Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling*.
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The antitumor activity of plant-derived non-psychoactive cannabinoids.
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The endocannabinoid system and cancer: therapeutic implication.
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The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
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The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells.
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United States patent application publication for phytocannabinoids in the treatment of cancer.
Cardiovascular
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Blood pressure regulation by endocannabinoids and their receptors.
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Cannabinoids in Experimental Stroke: A Systematic Review and Meta-Analysis.
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Is the cardiovascular system a therapeutic target for cannabidiol?
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Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation.
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Studies investigating the mechanisms of the cardioprotective effects of cannabidiol.
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Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke.
Cannabidiol
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Action of cannabidiol on the anxiety and other effects produced by Δ-9THC in normal subjects.
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Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action
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Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor.
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Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.
CB1-Receptor
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Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor.
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Enhanced acetylcholine release in the hippocampus of cannabinoid CB1 receptor-deficient mice.
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Evidence for functional CB1 cannabinoid receptor expressed in the rat thyroid.
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Immunohistochemical analysis of cannabinoid receptor 1 expression in steatotic rat livers.
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Loss of cannabinoid receptor 1 accelerates intestinal tumor growth.
CB2-Receptor
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Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus.
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CB2 cannabinoid receptors as an emerging target for demyelinating diseases.
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Direct suppression of autoreactive lymphocytes in the central nervous system via the CB2 receptor.
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Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation.
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Role of CB2 receptors in social and aggressive behavior in male mice.
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Targeting CB2 receptors and the endocannabinoid system for the treatment of pain.
CBDV
Cellular Function
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Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells.
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Cannabidiol, a therapeutic potential compound, inhibits the catalytic activity of cytochrome.
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Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels.
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Characterization of P-glycoprotein Inhibition by Major Cannabinoids from Marijuana.
Cerebral Palsy
Cognition
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Effects of cannabis on cognitive function in patients with multiple sclerosis.
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Methods of the Pharmacological Imaging of the Cannabinoid System (PhICS) study.
Colon Cancer
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Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor.
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Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines.
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Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors.
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Induction of Apoptosis by Cannabinoids in Prostate and Colon Cancer Cells Is Phosphatase Dependent.
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Possible endocannabinoid control of colorectal cancer growth.
Crohn's Disease
Depression
Diabetes
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Cannabidiol Arrests Onset of Autoimmune Diabetes in NOD Mice.
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Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.
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Novel Study Reports Marijuana Users Have Better Blood Sugar Control.
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Presence of functional cannabinoid receptors in human endocrine pancreas.
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The Endocannabinoid System and Plant-Derived Cannabinoids in Diabetes and Diabetic Complications.
Drug Interactions
Edema
Emesis
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Interaction between non-psychotropic cannabinoids in marihuana.
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The Effects of Cannabidiol and Tetrahydrocannabinol on Motion-Induced Emesis in Suncus murinus.
Endocannabinoid System
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Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids.
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An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors.
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Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.
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Cannabinoid receptors and endocannabinoids: Evidence for new players.
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Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain.
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Cannabis, a complex plant: different compounds and different effects on individuals.
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Cannabis and endocannabinoid modulators: Therapeutic promises and challenges.
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Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown.
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Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity.
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Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity.
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Modulating the endocannabinoid system in human health and disease - successes and failures.
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Recent advances in cannabinoid receptor agonists and antagonists.
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Role and Function of Endocannabinoid System in Major Depressive Disease.
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.
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The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.
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The Endocannabinoid System as an Emerging Target of Pharmacotherapy.
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The endocannabinoid system drives neural progenitor proliferation.
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The endocannabinoid system in normal and pathological brain ageing.
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The endogenous cannabinoid system and its role in nociceptive behavior.
Endocrine System
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Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines.
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Presence of functional cannabinoid receptors in human endocrine pancreas.
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.
Epilepsy
Fibrosis
Fybromalgia
Gastrointestinal Disease
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Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview.
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Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis.
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Cannabis use amongst patients with inflammatory bowel disease.
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Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism.
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Marijuana Use Patterns Among Patients with Inflammatory Bowel Disease.
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Treatment of Crohn's disease with cannabis: an observational study.
General
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Cannabis and Eicosanoids: A Review of Molecular Pharmacology.
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Cannabis sativa: The Plant of the Thousand and One Molecules.
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Chemical constituents of marijuana: The complex mixture of natural cannabinoids.
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Chemistry, metabolism, and toxicology of cannabis: clinical implications.
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Early phytocannabinoid chemistry to endocannabinoids and beyond.
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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
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Pharmacological actions and therapeutic uses of cannabis and cannabinoids.
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Phytocannabinoids beyond the Cannabis plant - do they exist?
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Plant cannabinoids: a neglected pharmacological treasure trove.
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Review on clinical studies with cannabis and cannabinoids 2010-2014.
Glaucoma
Glioblastoma
Glioma
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A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma.
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Cannabinoids as potential new therapy for the treatment of gliomas.
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Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression.
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Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas.
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Δ9-Tetrahydrocannabinol induces apoptosis in C6 glioma cells.
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Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
HIV
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Cannabinoid Receptor 2-Mediated Attenuation of CXCR4-Tropic HIV Infection in Primary CD4+ T Cells.
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Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial.
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Dronabinol and marijuana in HIV+ marijuana smokers: acute effects on caloric intake and mood.
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Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection.
Huntington's Disease
Immune Function
Infant Development
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Endocannabinoids, feeding and suckling – from our perspective.
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The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.
Psychedelic Therapy
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A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers.
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A potential role for psilocybin in the treatment of obsessive-compulsive disorder.
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Beckley Foundation for research into cannabis & psychedelics.
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Classical psychedelics for the treatment of depression and anxiety: A systematic review.
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MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study.
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Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm.
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Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.
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Psilocybin with psychological support for treatment-resistant depression: six-month follow-up.
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Reviewing the Potential of Psychedelics for the Treatment of PTSD.
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Spontaneous and deliberate creative cognition during and after psilocybin exposure.
Skin