Clinical Resources
ADHD
Addiction
Alzheimers Disease
Anxiety
Appetite
Arthritis
Asthma
Autism
Autoimmune
Batten Disease
Breast Cancer
Cancer
Cannabidiol
Cardiovascular
CB1 - Receptor
CB2 - Receptor
CBDV
Cellular Function
Cerebral Palsy
Cognition
Colon Cancer
Crohn's Disease
Depression
Diabetes
Drug Interactions
Edema
Emesis
Endocannabinoid System
Endocrine System
Epilepsy
Fibrosis
Fybromalgia
Gastrointestinal Disease
General
Glaucoma
Glioblastoma
Glioma
HIV
Huntington's Disease
Immune Function
Infant Development
Psychedelic therapy
Skin
ADHD
Addiction
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Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence.
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Cannabidiol (CBD) in cannabis does not impair driving, landmark study shows.
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Interactions between Δ(9)-tetrahydrocannabinol and heroin: self-administration in rhesus monkeys.
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Involvement of the endocannabinoid system in drug addiction.
Alzheimer's Disease
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A Molecular Link between the Active Component of Marijuana and Alzheimer's Disease Pathology.
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Cannabinoids and Dementia: A Review of Clinical and Preclinical Data.
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Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic.
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Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia.
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Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview.
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Synthetic Cannabinoids in Dementia with Agitation: Case Studies and Literature Review.
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The influence of cannabinoids on generic traits of neurodegeneration.
Anxiety
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Action of cannabidiol on the anxiety and other effects .produced by delta 9-THC in Normal Subjects.
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Is cannabis treatment for anxiety, mood, and related disorders ready for prime time?
Appetite
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Endocannabinoids, feeding and suckling – from our perspective.
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Endogenous cannabinoid system as a modulator of food intake.
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Hypothalamic POMC neurons promote cannabinoid-induced feeding.
Arthritis
Asthma
Autism
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Alterations in the endocannabinoid system in the rat valproic acid model of autism.
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Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling.
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Endocannabinoid System as Novel Therapeutic Target for Autism Treatment.
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Method for predicting autism spectrum disorders by cannabinoid and cannabinoid receptor expression.
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Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome.
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Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces.
Autoimmune
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Cannabidiol arrests onset of autoimmune diabetes in NOD mice.
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Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
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Cannabis use in people with Parkinson’s disease and Multiple Sclerosis: A web-based investigation.
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Endocannabinoids and the Immune System in Health and Disease.
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Endocannabinoid system acts as a regulator of immune homeostasis in the gut.
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Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly.
Batten disease
Breast Cancer
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Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
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Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.
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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
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The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
Cancer
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A Cannabinoid Quinone Inhibits Angiogenesis by Targeting Vascular Endothelial Cells.
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Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors.
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Anti-proliferative effects of anandamide in human hepatocellular carcinoma cells.
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Cannabidiol (CBD) Priming Enhances Cisplatin Killing Of Cancer Cells.
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Cannabidiol Inhibits Growth and Induces Programmed Cell Death in Kaposi Sarcoma.
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Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
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Cannabinoid-associated cell death mechanisms in tumor models.
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Cannabinoid receptor ligands as potential anticancer agents — high hopes for new therapies?
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Cannabinoid receptors as novel targets for the treatment of melanoma.
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Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators.
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COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells.
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Differential role of cannabinoids in the pathogenesis of skin cancer.
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Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders.
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Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion.
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Expression and Functional Relevance of Cannabinoid Receptor 1 in Hodgkin Lymphoma.
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Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma.
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In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
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Involvement of PPARc in the antitumoral action of cannabinoids on hepatocellular carcinoma.
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Loss of cannabinoid receptor 1 accelerates intestinal tumor growth.
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Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers.
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Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid.
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Proapoptotic effect of endocannabinoids in prostate cancer cells.
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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.
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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
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Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling*.
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The antitumor activity of plant-derived non-psychoactive cannabinoids.
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The endocannabinoid system and cancer: therapeutic implication.
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The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.
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The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells.
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United States patent application publication for phytocannabinoids in the treatment of cancer.
Cardiovascular
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Blood pressure regulation by endocannabinoids and their receptors.
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Cannabinoids in Experimental Stroke: A Systematic Review and Meta-Analysis.
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Is the cardiovascular system a therapeutic target for cannabidiol?
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Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation.
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Studies investigating the mechanisms of the cardioprotective effects of cannabidiol.
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Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke.
Cannabidiol
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Action of cannabidiol on the anxiety and other effects produced by Δ-9THC in normal subjects.
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Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action
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Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor.
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Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.
CB1-Receptor
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Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor.
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Enhanced acetylcholine release in the hippocampus of cannabinoid CB1 receptor-deficient mice.
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Evidence for functional CB1 cannabinoid receptor expressed in the rat thyroid.
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Immunohistochemical analysis of cannabinoid receptor 1 expression in steatotic rat livers.
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Loss of cannabinoid receptor 1 accelerates intestinal tumor growth.
CB2-Receptor
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Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus.
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CB2 cannabinoid receptors as an emerging target for demyelinating diseases.
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Direct suppression of autoreactive lymphocytes in the central nervous system via the CB2 receptor.
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Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation.
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Role of CB2 receptors in social and aggressive behavior in male mice.
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Targeting CB2 receptors and the endocannabinoid system for the treatment of pain.
CBDV
Cellular Function
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Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells.
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Cannabidiol, a therapeutic potential compound, inhibits the catalytic activity of cytochrome.
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Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels.
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Characterization of P-glycoprotein Inhibition by Major Cannabinoids from Marijuana.
Cerebral Palsy
Cognition
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Effects of cannabis on cognitive function in patients with multiple sclerosis.
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Methods of the Pharmacological Imaging of the Cannabinoid System (PhICS) study.
Colon Cancer
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Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor.
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Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines.
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Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors.
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Induction of Apoptosis by Cannabinoids in Prostate and Colon Cancer Cells Is Phosphatase Dependent.
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Possible endocannabinoid control of colorectal cancer growth.
Crohn's Disease
Depression
Diabetes
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Cannabidiol Arrests Onset of Autoimmune Diabetes in NOD Mice.
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Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.
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Novel Study Reports Marijuana Users Have Better Blood Sugar Control.
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Presence of functional cannabinoid receptors in human endocrine pancreas.
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The Endocannabinoid System and Plant-Derived Cannabinoids in Diabetes and Diabetic Complications.
Drug Interactions
Edema
Emesis
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Interaction between non-psychotropic cannabinoids in marihuana.
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The Effects of Cannabidiol and Tetrahydrocannabinol on Motion-Induced Emesis in Suncus murinus.
Endocannabinoid System
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Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids.
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An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors.
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Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.
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Cannabinoid receptors and endocannabinoids: Evidence for new players.
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Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain.
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Cannabis, a complex plant: different compounds and different effects on individuals.
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Cannabis and endocannabinoid modulators: Therapeutic promises and challenges.
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Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown.
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Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity.
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Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity.
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Modulating the endocannabinoid system in human health and disease - successes and failures.
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Recent advances in cannabinoid receptor agonists and antagonists.
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Role and Function of Endocannabinoid System in Major Depressive Disease.
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.
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The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.
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The Endocannabinoid System as an Emerging Target of Pharmacotherapy.
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The endocannabinoid system drives neural progenitor proliferation.
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The endocannabinoid system in normal and pathological brain ageing.
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The endogenous cannabinoid system and its role in nociceptive behavior.
Endocrine System
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Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines.
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Presence of functional cannabinoid receptors in human endocrine pancreas.
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance.
Epilepsy
Fibrosis
Fybromalgia
Gastrointestinal Disease
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Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview.
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Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis.
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Cannabis use amongst patients with inflammatory bowel disease.
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Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism.
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Marijuana Use Patterns Among Patients with Inflammatory Bowel Disease.
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Treatment of Crohn's disease with cannabis: an observational study.
General
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Cannabis and Eicosanoids: A Review of Molecular Pharmacology.
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Cannabis sativa: The Plant of the Thousand and One Molecules.
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Chemical constituents of marijuana: The complex mixture of natural cannabinoids.
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Chemistry, metabolism, and toxicology of cannabis: clinical implications.
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Early phytocannabinoid chemistry to endocannabinoids and beyond.
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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
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Pharmacological actions and therapeutic uses of cannabis and cannabinoids.
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Phytocannabinoids beyond the Cannabis plant - do they exist?
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Plant cannabinoids: a neglected pharmacological treasure trove.
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Review on clinical studies with cannabis and cannabinoids 2010-2014.
Glaucoma
Glioblastoma
Glioma
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A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma.
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Cannabinoids as potential new therapy for the treatment of gliomas.
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Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression.
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Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas.
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Δ9-Tetrahydrocannabinol induces apoptosis in C6 glioma cells.
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Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
HIV
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Cannabinoid Receptor 2-Mediated Attenuation of CXCR4-Tropic HIV Infection in Primary CD4+ T Cells.
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Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial.
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Dronabinol and marijuana in HIV+ marijuana smokers: acute effects on caloric intake and mood.
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Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection.
Huntington's Disease
Immune Function
Infant Development
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Endocannabinoids, feeding and suckling – from our perspective.
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The endocannabinoid-CB receptor system: Importance for development and in pediatric disease.
Psychedelic Therapy
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A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers.
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A potential role for psilocybin in the treatment of obsessive-compulsive disorder.
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Beckley Foundation for research into cannabis & psychedelics.
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Classical psychedelics for the treatment of depression and anxiety: A systematic review.
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MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study.
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Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm.
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Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.
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Psilocybin with psychological support for treatment-resistant depression: six-month follow-up.
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Reviewing the Potential of Psychedelics for the Treatment of PTSD.
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Spontaneous and deliberate creative cognition during and after psilocybin exposure.
Skin