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Safety

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death

Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine

Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up

Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS)

CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity

Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity

Δ9-Tetrahydrocannabinol Prevents Methamphetamine-Induced Neurotoxicity

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study

Endocannabinoid signaling in neurotoxicity and neuroprotection

Molecular Mechanisms of Cannabinoid Protection from Neuronal Excitotoxicity

Neuroprotection by Δ9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes

Neuroprotective Effect of(−)Δ9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d-Aspartate-Induced Retinal Neurotoxicity

Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on b-amyloid-induced toxicity in PC12 cells

Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity

Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism

Protective effect of cannabidiol against cadmium hepatotoxicity in rats

Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma

Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent

Safety and Toxicology of Cannabinoids

Skeletal System

Activation of Cannabinoid Receptor 2 Enhances Osteogenic Differentiation of Bone Marrow Derived Mesenchymal Stem Cells

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

Cannabinoid receptors and the regulation of bone mass

Cannabinoids and bone: endocannabinoids modulate human osteoclast function
in vitro

Cannabinoids and the skeleton: From marijuana to reversal of bone loss

Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone

Peripheral cannabinoid receptor, CB2, regulates bone mass

Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration

Role of cannabinoids in the regulation of bone remodeling

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

The Role of Type 2 Cannabinoid Receptor in Bone Metabolism

Sleep

Administration of URB597, Oleoylethanolamide or Palmitoylethanolamide Increases Waking and Dopamine in Rats

A Longitudinal Study of Prenatal Marijuana Use

A Pilot Study into the Effects of the CB1 Cannabinoid Receptor Agonist WIN55,212-2 or the Antagonist/Inverse Agonist AM251 on Sleep in Rats

Around‐the‐Clock Oral THC Effects on Sleep in Male Chronic Daily Cannabis Smokers

Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis

Cannabidiol in Anxiety and Sleep: A Large Case Series

(−)δ9 THC as an hypnotic

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Effect of Δ-9-Tetrahydrocannabinol and Cannabidiol on Nocturnal Sleep and Early-Morning Behavior in Young Adults

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana

Endocannabinoid Signaling Regulates Sleep Stability

Functional Role for Cannabinoids in Respiratory Stability During Sleep

Intrahippocampal administration of anandamide increases REM sleep

Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat

Modulation of Sleep-Wake Cycles in Mice and Rats with Cannabinoids 

Potential Effects of Cannabidiol as a Wake-Promoting Agent

Proof of concept trial of dronabinol in obstructive sleep apnea

The effects of cannabinoid administration on sleep: a systematic review of human studies

The Emerging Role of the Endocannabinoid System in the Sleep-Wake Cycle Modulation 

The Nonpsychoactive Cannabis Constituent Cannabidiol Is a Wake-Inducing Agent

Spasticity

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex®), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis

Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

Cannabinoids in the management of spasticity associated with multiple sclerosis

Clinical experiences with cannabinoids in spasticity management in multiple sclerosis

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study

Sativex in the Management of Multiple Sclerosis-Related Spasticity: Role of the Corticospinal Modulation

Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial

Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity

Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review

Sports

Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion

Acute upregulation of neuronal mitochondrial type-1 cannabinoid receptor and it’s role in metabolic defects and neuronal apoptosis after TBI

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

Cannabidiol administration after hypoxia–ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function

Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury

Cannabidiol­ treated rats exhibited higher motor score after cryogenic spinal cord injury.

Cannabinoid agonist rescues learning and memory after a traumatic brain injury

Cannabinoid CB2 Receptor Activation Attenuates Motor and Autonomic Function Deficits in a Mouse Model of Spinal Cord Injury

Cannabinoids and the skeleton: From marijuana to reversal of bone loss

Cannabis Responsive Head Injury Induced Mutiple Disabilities: A Case Report

CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced
Neuroprotection Following Traumatic Brain Injury in Mice

CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced
Neuroprotection Following Traumatic Brain Injury in Mice

Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet

Effects of Cannabidiol and Hypothermia on Short-Term Brain Damage in New-Born Piglets after Acute Hypoxia-Ischemia

Endocannabinoids and traumatic brain injury

Estradiol Decreases Cortical Reactive Astrogliosis after Brain Injury by a Mechanism
Involving Cannabinoid Receptors

HU­211, a Novel Noncompetitive N­Methyl­D­Aspartate Antagonist, Improves Neurological Deficit and Reduces Infarct Volume After Reversible Focal Cerebral Ischemia in the Rat

Injury, Pain, and Prescription Opioid Use Among Former National Football League (NFL) Players*

Mechanisms of cannabidiol neuroprotection in hypoxiceischemic newborn pigs:
Role of 5HT1A and CB2 receptors

Peripheral cannabinoid receptor, CB2, regulates bone mass

Tissue Engineering of Cartilage; Can Cannabinoids Help? 

Role of cannabinoids in the regulation of bone remodeling

The Cannabinoid Agonist Win55212 Reduces Brain Damage in an In Vivo Model of Hypoxic-Ischemic Encephalopathy in Newborn Rats

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling

The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke

The Role of Type 2 Cannabinoid Receptor in Bone Metabolism

Update on the Role of Cannabinoid Receptors after Ischemic Stroke

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